Your real heart risk, measured instead of guessed
Almost nobody books cardiovascular testing out of idle curiosity. It is usually a question that will not leave you alone, and this pathway exists to answer it with measurement instead of reassurance: the markers that predict risk years ahead, the imaging that shows what is actually there, and a biological age estimate tracked honestly over time.
- My father died of a heart attack at 55. Is the same thing coming for me?
- My cholesterol came back normal, but I do not trust one number.
- Sometimes my heart races, and every ECG at the GP looks fine.
- I feel completely healthy. So did my uncle.
Every one of those has a measurable answer, and getting it starts with a free call.
Function and structure, not just a risk calculator
Advanced lipid and inflammation markers
Results explained by a physician, in person
Why these markers, and not just cholesterol
Each of these captures risk that a routine panel provably misses:
- ApoB counts the particles that cause the disease; standard cholesterol only weighs them. In 389,529 UK Biobank adults, it was the one lipid number that stayed predictive when the others were accounted for (Marston 2022)
- Lp(a) is an inherited, causal risk factor a standard panel never measures. European consensus now recommends every adult have it tested at least once, and one measurement usually settles it for life (Kronenberg 2022)
- Inflammation predicts events cholesterol cannot see: in 31,245 statin-treated patients, residual inflammation predicted cardiovascular death far more strongly than residual cholesterol did (Ridker 2023)
- High-sensitivity troponin finds silent heart muscle injury in people who feel fine, invisible to standard assays (de Lemos 2010)
- On carotid ultrasound, what matters is visible plaque, which predicts events better than any thickness measurement (Inaba 2012)
How your heart is assessed
Cardiac testing at AION covers rhythm, structure and how your heart performs under load:
- ECG and echocardiogram for rhythm and structure
- Stress ECG to see how your heart performs under exertion
- Holter monitoring and ambulatory blood pressure over a full day
- Carotid ultrasound to check for early vascular changes
Beyond a standard cholesterol panel
Standard cholesterol tells an incomplete story. AION also looks at markers that carry more predictive weight:
- ApoB and Lp(a), which reflect the number of atherogenic particles more accurately than standard cholesterol
- High-sensitivity troponin and inflammatory markers such as hs-CRP
- Your personal and family history, weighed alongside the numbers, not instead of them
Testing your biological age, with honest error bars
Biological age testing measures ageing at the cellular level, using epigenetic and telomere markers. The population-level science is genuinely strong: people who measure older than their birth date die earlier, at the scale of hundreds of thousands studied. The individual-level honesty is that a single person's number carries a real error margin, so AION presents it as an exploratory estimate tracked against your own baseline, never as a verdict.
- Epigenetic (DNA methylation) age testing
- Telomere length testing
- Compared against your own baseline at your next assessment
- Framed as an estimate with an error margin, because that is what it is
Questions about cardiovascular & biological age
ECG, echocardiogram, stress ECG, Holter and ambulatory blood pressure monitoring, carotid ultrasound, and blood markers including ApoB, Lp(a), high-sensitivity troponin and inflammation markers.
It measures ageing at a cellular level, using epigenetic and telomere markers, so you get a picture of how your body is actually ageing rather than an estimate based on your date of birth.
No. Your physician selects what is relevant based on your history, family risk and initial assessment. Nothing here is run as a fixed package regardless of who you are.
A routine check-up usually stops at standard cholesterol and a resting ECG. This pathway adds the markers and imaging that catch risk years earlier, and a physician interprets all of it together, not test by test.
At the population level, yes: methylation age predicts mortality across large cohorts. At the individual level, honestly, the number carries meaningful technical noise, and no trial has yet shown that lowering your measured epigenetic age lowers your risk. AION treats it as an interesting, trackable estimate, and puts the clinical weight on the markers with hard evidence behind them.
Related clinical evidence
View the full clinical evidence library →The evidence behind Cardiovascular & Biological Age
Coronary Artery Calcium Scoring: What the Evidence Actually Supports
Arterial Stiffness and Pulse Wave Velocity: An Adjunct Risk Marker, Not a Standalone Screen
Cardiorespiratory Fitness (VO2max) as a Vital Sign for Mortality Risk
Epigenetic and Biological Age Clocks: Correlative Research Tool or Clinical Test?
Connected care
One body. Everything connects.
What you've just read is rarely the whole story. These are often part of the same picture.
AION
Longevity Clinic
Standard medicine, applied years earlier and read by a physician. That is the whole idea, and AION practices it without the hype.
Treatment
Plasma Exchange
A medical procedure for specific diagnosed conditions, from CIDP to myasthenia gravis, performed only where the evidence and your physician support it.
Program
Longevity AION 360
Where is your health heading, measured directly instead of guessed at.
Find out if this diagnostic pathway is your answer.
One free call. You leave knowing whether AION fits your case, what it would involve, and what it costs. If the honest answer is no, you hear that too, and it costs you nothing to hear it.
Your free call is with Dr Inbar Almon Tofan, AION Department Manager, and Sylvia, Patient Coordinator. It is a first conversation, not a medical consultation.